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Department of Medical Microbiology, University Hospital Maastricht, Medical Microbiology, P.O. Box 5800, 6202AZ Maastricht; 4Department of General Practice, University of Maastricht, Maastricht, The Netherlands 2 Department of Biology, Haverford College, Haverford, PA, USA; 3Kenya Medical Research Institute, Nairobi, Kenya.

4: 41PM EF.00003 Electrowetting-induced oil film entrapment and instability , ADRIAN STAICU, FRIEDER MUGELE, Physics of Complex Fluids, University of Twente -- Electrowetting is a classic example of interaction between fluids and electric fields: by applying a voltage between a drop of conductive liquid and an insulator-covered hydrophobic electrode, the contact angle of the drop can be reduced by several tens of degrees compared to Young's angle F. Mugele and J.-C. Baret, J. Phys.: Condens. Matter 17, R705, 2005 ; . We investigate the spreading at variable rate of a water drop on a smooth hydrophobic substrate in an ambient oil bath driven by electrowetting. We find that a thin film of oil is entrapped under the drop. Its thickness is described by an extension of the Landau-Levich law of dip coating that includes the electrostatic pressure contribution. Once trapped, the thin film becomes unstable under the competing effects of the electrostatic pressure and surface tension and dewets into microscopic droplets, in agreement with a linear stability analysis. By varying the thickness of the dielectric layer, we expect to be able to tune the relative importance of the electrostatic contribution in future experiments. Our results recommend electrowetting as an efficient experimental approach to the problem of dynamic wetting in the presence of a tunable substrate-liquid interaction. 4: 54PM EF.00004 Dynamics of Oscillating and Rotating Liquid Drop using Electrostatic Levitator , SATOSHI MATSUMOTO, Japan Aerospace Exploration Agency, SHIGERU AWAZU, University of Tsukuba, YUTAKA ABE, TADASHI WATANABE. 2005 denying all claims contained therein doc. 5 ; . Schwarz Pharma then filed the current Motion before the Court doc. 7 ; . Howard was employed by Schwarz Pharma from March 5, 1997 until February 19, 2003 doc. 1 ; . Howard's Complaint are as follows. The facts as alleged in. What is diverticulosis? A diverticulum singular ; is an out-pouching of the wall of the gastrointestinal tract to form a sac. Diverticula plural ; may occur at any level involving the esophagus, stomach, small bowel and large bowel colon ; . The diverticula discussed herein are colonic diverticula. Diverticulosis means there are pockets or projections extending out from the wall of the colon. These occur very gradually over a long period of time and are, therefore, more common in the elderly. They occur along naturally weak points in the bowel wall which often coincide with perforating blood vessels bringing blood to the inner lining of the colon. The pockets develop because of the pressure exerted within the contracting colon. Since the sigmoid colon has the highest pressure in the colon, it is here that most diverticula occur. Because of these balloon-like projections and high pressures, the sigmoid often becomes thickened and narrowed over time just as any other muscle working overtime would become thickened. This narrowing can cause significant changes in bowel function such as discomfort, diarrhea and or constipation. Who gets diverticulosis? We are all born without colonic diverticula. Since it takes so long to develop, diverticulosis usually appears later in life. It is not uncommon, however, to see people who have diverticulosis in their 30s or 40s. Generally, 50% of men and women over the age of 60 develop at least one, usually a few dozen, diverticula. Eventually the colon, especially the sigmoid colon, becomes studded with these pockets. This disorder is mostly one of western society and is generally attributable to a diet low in fiber. These small out pouchings are much less common in life-long vegetarians. Diverticulosis is uncommon in rural Africa, India and many parts of Asia where diets consist largely of unprocessed foods, grains and have a very high fiber content.

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Based upon wartime requirements establishes the conditions for the specific Swedish version of social division among the peasantry, and thus carries far-reaching sociostructural implications as well, affecting the peculiar set of class-specific property rights as well as the conditions of political representation, including, specifically, the choice-set of political alliances. The `freezing' of the land nature distribution is not a consequence of the rebellion as such; it had been achieved already through the rfst inquiry into alienated Crown estates ; of Queen Margaret Cf Rosn 1950 ; , the result of a com-promise between the Queen and the group of magnates who had offered her the Crown. Through accepting her authority to resume Crown goods they got the chance to influence the realization and conditions of this reduction230 in their capacity of experienced judges231. The formative moment I discern in the aftermath of the rebellion, is thus not the first emergence of this `frozen distribution' it is that the aristocracy controlling the state at this moment accepted the twosector model and took measures to preserve the balance. This compromise between short-term individual and long-term collective interests provided the foundation for the kind of `collective kingship' exercised by oligarchic assemblies at recurring moments in the further development. From this point onwards, the roughly fixed-proportion division between: a `public sector' providing the material basis for the protostate through fixed land taxes and a `private' seigneurial sector providing the material basis for the ruling class through more or less contractual rents232, seems to have led to something like a `two-sided Bauernschutz policy' or a `competition in protection'. Instead of engaging in a. Further implement York's brand strategy through compelling, consistent and integrated communications To produce further integrated communications solutions for 5-10 university units, as has already been achieved for Research, Atkinson, Admissions, Alumni and the Tennis event amongst others. Establish partnership arrangements with additional administrative and academic units and methazolamide. 1. Ho, D. D., Neumann, A. U., Perelson, A. S., Chen, W., Leonard, J. M., Markowitz, M. 1995 ; Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 373, 123126. 2. Orenstein, J. M., Fox, C., Wahl, S. M. 1997 ; Macrophages as a source of HIV during opportunistic infections. Science 276, 18571861. 3. Gorantla, S., Che, M., Gendelman, H. E. 2005 ; Isolation, propagation, and HIV-1 infection of monocyte-derived macrophages and recovery of virus from brain and cerebrospinal fluid. Methods Mol. Biol. 304, 35 48. Stout, R. D., Suttles, J. 2004 ; Functional plasticity of macrophages: reversible adaptation to changing microenvironments. J. Leukoc. Biol. 76, 509 513. Rosenberg, Z. F., Fauci, A. S. 1990 ; Immunopathogenic mechanisms of HIV infection: cytokine induction of HIV expression. Immunol. Today 11, 176 180. Fantuzzi, L., Belardelli, F., Gessani, S. 2003 ; Monocyte macrophagederived CC chemokines and their modulation by HIV-1 and cytokines: a complex network of interactions influencing viral replication and AIDS pathogenesis. J. Leukoc. Biol. 74, 719 725. Graziosi, C., Gantt, K. R., Vaccarezza, M., Demarest, J. F., Daucher, M., Saag, M. S., Shaw, G. M., Quinn, T. C., Cohen, O. J., Welbon, C. C., Pantaleo, G., Fauci, A. S. 1996 ; Kinetics of cytokine expression during primary human immunodeficiency virus type 1 infection. Proc. Natl. Acad. Sci. USA 93, 4386 4391. Poli, G., Biswas, P., Fauci, A. S. 1994 ; Interferons in the pathogenesis and treatment of human immunodeficiency virus infection. Antiviral Res. 24, 221233. 9. Bleul, C. C., Farzan, M., Choe, H., Parolin, C., Clark-Lewis, I., Sodroski, J., Springer, T. A. 1996 ; The lymphocyte chemoattractant SDF-1 is a ligand for LESTR fusin and blocks HIV-1 entry. Nature 382, 829 833. Raport, C. J., Gosling, J., Schweickart, V. L., Gray, P. W., Charo, I. F. 1996 ; Molecular cloning and functional characterization of a novel human CC chemokine receptor CCR5 ; for RANTES, MIP-1 , and MIP-1 . J. Biol. Chem. 271, 1716117166. 11. Samson, M., Labbe, O., Mollereau, C., Vassart, G., Parmentier, M. 1996 ; Molecular cloning and functional expression of a new human CC-chemokine receptor gene. Biochemistry 35, 33623367. 12. Vives, R. R., Imberty, A., Sattentau, Q. J., Lortat-Jacob, H. 2005 ; Heparan sulfate targets the HIV-1 envelope glycoprotein gp120 coreceptor binding site. J. Biol. Chem. 280, 2135321357. 13. Bobardt, M. D., Saphire, A. C., Hung, H. C., Yu, X., Van der Schueren, B., Zhang, Z., David, G., Gallay, P. A. 2003 ; Syndecan captures, protects, and transmits HIV to T lymphocytes. Immunity 18, 2739. 14. Turville, S. G., Vermeire, K., Balzarini, J., Schols, D. 2005 ; Sugarbinding proteins potently inhibit dendritic cell human immunodeficiency virus type 1 HIV-1 ; infection and dendritic-cell-directed HIV-1 transfer. J. Virol. 79, 13519 13527. Chehimi, J., Luo, Q., Azzoni, L., Shawver, L., Ngoubilly, N., June, R., Jerandi, G., Farabaugh, M., Montaner, L. J. 2003 ; HIV-1 transmission and cytokine-induced expression of DC-SIGN in human monocyte-derived macrophages. J. Leukoc. Biol. 74, 757763. 16. Geijtenbeek, T. B., Kwon, D. S., Torensma, R., van Vliet, S. J., van Duijnhoven, G. C., Middel, J., Cornelissen, I. L., Nottet, H. S., KewalRamani, V. N., Littman, D. R., Figdor, C. G., van Kooyk, Y. 2000 ; DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell 100, 587597. 17. Turville, S., Wilkinson, J., Cameron, P., Dable, J., Cunningham, A. L. 2003 ; The role of dendritic cell C-type lectin receptors in HIV pathogenesis. J. Leukoc. Biol. 74, 710 718.

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You'll come to Vidish, the capital Well known across the compass of these quarters, When, like a lover, at the Vetravati, Hang on her face to have the frowning waters Turn to murmuring, and drink your fill. Rest on Nichais mountain. At your touch Kadamba flowers will bristle out as hair, And grottos give out odours, those by which The venal women of the town ensnare A roistering youth who have no sense as such. Refreshed, upon the forest river tiers Of jasmine, sprinkle moisture you have gained, And on the female garland-makers, shading Those who, brushing faces sweat has stained, Have hurt the lotus blossoms in their ears. Circuitous your path: if not received With tumult in the palaces of Ujjain By women sidelong glittering in their eyelids, Your lightning's sweep and dazzlement has been By their eyes' allurement much deceived. From undulating lines of birds above The extended water's loquacious girdle string, See the Nirvandhy reveal her navel And, like a woman passed from dallying In gestured overtures, declare her love. From dwindled to a single braid of hair, And pale with old leaves fallen on her banks, So will the Sindhu cast off separation And from her thinness correspond with thanks: How fortunate to pass her needful there and methimazole.
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Anti-baldness hair loss hair replacement such as Rogaine, but only if to replace hair loss due to a medical condition e.g. cancer treatment ; and not for balding due to age Fiber supplements such as Benefiber and Metamucil Glucosamine Chondrotin for arthritis or other medical condition not reimbursable if taken for overall joint health ; Herbal supplements used to treat a specific disease such as St. John's Wort for depression Hormone Therapy Drugs Medicated shampoos' to treat a specific medical condition like psoriasis and only the amount in excess of the cost of normal shampoo No Doz and other sleep prevention drugs ; Nose strips for proper breathing or other medical conditions Pedialyte for a child's dehydration Retin-A and other acne medicines not reimbursable if used for cosmetic purposes such as wrinkle reduction ; Sleep-Aids Snoring cessation aids and medications such as Breathe Right Spray, Snorezz Sunscreen and Sunblock Vitamins are not an eligible expense, unless prescribed by a physician to treat a specific medical condition. i.e. Iron to treat, not prevent, anemia; Calcium supplements to treat, not prevent, Osteoporosis ; . A doctor's note detailing the specific medical condition will be required for reimbursement. Weight loss dietary supplements must be for a specific medical condition such as obesity and methocarbamol. Conventional clotting studies are usually performed on centrifuged plasma fractions and therefore only provide information on isolated parts of the coagulation cascade. There are several interactions between constituent parts of the clotting cascade, and proper clinical evaluation of clotting and bleeding problems requires information regarding these interactions which is not provided routinely by haematology laboratories [24]. Most of the conventional tests end when fibrin strands are formed but viscoelastic techniques such as Sonoclot begin as the first fibrin strands become evident and continue through to clot lysis and retraction. No studies have shown a direct correlation between abnormalities in the conventional clotting tests and perioperative blood loss, probably because adequate platelet function is required before normal haemostasis can occur. A normal platelet count does not imply that platelet function is normal, but platelet function tests are complex and unsuitable for acute perioperative situations requiring rapid diagnosis and treatment. SCT distinctly differentiates between platelet-rich and platelet-poor plasma [34] and has been used primarily for assessing platelet function [29]. Tuman and colleagues [38] found that the sensitivity of SCT in predicting postoperative bleeding after cardiopulmonary bypass was 74 %, with no false negatives and 33 % false positives. This compares well with a predictive accuracy of 33 % using routine coagulation tests, with 44 % false negative results and 73 % false positive results. Chapin and co-workers [5] found that SCT diagnosis of platelet dysfunction or clotting factor deficiency correlated well with the results of standard coagulation tests during liver transplantation. Defects of fibrinolysis have been implicated increasingly as a cause of perioperative bleeding [14, 28], Sonoclot is not a better test of fibrinolytic activity than routine tests such as measurement of fibrin degradation products, but it may produce results more quickly and prove to be a useful guide to intraoperative fibrinolytic activity. However, TEG is more useful as a monitor of this aspect of coagulation function. SCT provides dynamic information on the coagulation pathway that is not available from conventional tests and therefore offers a method of rationalizing the management of perioperative bleeding problems.

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How healthy is GSK's pipeline of potential new medicines? JPG. We currently have 54 New Chemical Entities NCEs ; in Phases II and III late stage ; clinical trials, and have achieved good results over the last few months from studies of some of our key compounds, including lapatinib for cancer and Cervarix, a vaccine against cervical cancer. A lot remains to be done, of course, and there will always be some pipeline attrition, but we are making good progress. We believe we have one of the largest and most promising pipelines in the industry in fact, the number of NCEs in the pipeline has increased by nearly 80% since the merger. In 2005, data are expected on at least 15 products and vaccines in Phase II clinical trials, including compounds to treat HIV, diabetes, blood disorders and multiple sclerosis. In the meantime, can GSK continue to deliver strong performance? JPG. We have been able to stay on track financially because of the performance of our key pharmaceutical products, such as Seretide Advair and Avandia. We have also done very well with products such as Coreg for heart failure and Lamictal for epilepsy and bipolar disorder, Valtrex for genital herpes and our vaccines business. These products grew 22% in 2004 and methotrexate On the next page is a sample of a complete connection circle with causality arrows drawn. Notice that arrows frequently cross, making the diagram somewhat confusing to follow. Connection circles begin as brainstorming tools and can get messy and metamucil.

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